Let’s dig in. The active ingredient in aspirin is acetylsalicylic acid, which is chemically similar to salicylic acid, a naturally occurring compound in plants. Salicylic acid plays a crucial ...

After oral administration, aspirin is rapidly hydrolyzed in the plasma to salicylic acid so that plasma levels of aspirin are undetectable 1-2 hours after dosing. Peak plasma levels of salicylic ...

It is also referred to as acetylsalicylic acid (ASA) and salicylic acid. Aspirin has a very short half-life, meaning it is ...

The long history of aspirin and other pain relievers emphasizes ... the benefits of willow bark extract, and in the 1820s salicylic acid was identified as the bark's active component.

It was later discovered that the active ingredient was salicylic acid. This was modified by chemists into the substance we call aspirin, which is less irritating to the stomach than salicylic acid.

DeBakey VA Medical Center. For example, Jneid said aspirin can begin to break down into acetic acid and salicylic acid, both of which can irritate the stomach and not have the intended medicinal ...