The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein is critical for membrane fusion and eventual viral infection. Enveloped viruses use highly specific protein machinery ...

The spike is the entry key that allows SARS-CoV-2 into human cells. Changes in the virus' genome, which affect the spike's structure, therefore have potential to make the virus either more or less ...

A SARS-CoV-2 infection begins when the virus’s spike proteins bind to ACE2 cell surface receptors, enabling the virus to infect human cells. This key event of the receptor binding is followed by ...

The rod-like spike proteins on the surface of SARS CoV-2 are the tip of the spear of the ... Children's Division of Molecular Medicine established the structure of the spike protein, both before ...

When this structure gets bound by a specific bundle ... This process kicks off when the SARS-CoV-2 spike protein binds to our lung cells’ ACE2 receptors. They decided to call the hairpin loop ...

Researchers studying SARS-CoV-2, the novel coronavirus that causes ... researcher who published the first cryo-EM structure of the spike protein last month, says RdRp is the only other protein ...

The virions have a similar structure to natural viruses but ... the effect of inflammatory fatty acids on the spike protein of SARS-CoV-2. Inflammatory fatty acids are released during any ...

The SARS-CoV-2 virus is continuously evolving ... The researchers summarized the structure-based classification of the spike protein receptor-binding domains (RBD) that target antibodies to ...

Although people typically think of the spike protein ... The SARS-CoV-2 virus has three kinds of genes -- those involved in making more copies of the virus, those that make the virus structure ...

In mouse models and human postmortem samples, SARS-CoV-2 spike protein was found in the skull marrow, meninges, and parenchyma, according to Ali Ertürk, PhD, of the Helmholtz Center Munich in ...