Major activating receptors on NK cells, including NKG2D and the natural cytotoxicity receptors (NCRs) NKp30, NKp44 and NKp46, recognize pathogen-derived or self ‘stress’ molecules on diseased ...

The innate immune system consists of all the immune ... which in the case of the α/β T-cell receptor recognize a complex formed by a peptide seated within the groove of an MHC molecule. 2,31 ...

The expression of CD80 and CD86 molecules on the surface of the antigen-presenting cell is controlled by the innate immune system. Receptors such as TLRs induce these molecules to appear on the ...

How immune cells recognize their enemies Date: December 8, 2023 ... However, further analyses of the interaction between the BTN molecules and the receptors of the Vγ9Vδ2 T cells are still required.

This is part three of a series on the immune processes that protect our gut in the face of SARS-CoV-2 and other infections. Here, we give an overview of innate lymphoid cells (ILCs), a recently ...

The T-cells and B-cells in this system have receptors that recognize specific foreign antigens, and they develop long-lasting immune memory to protect against future infections or cancers.

Roybal and colleagues created sensors on the surface of immune cells, for example, that recognized tumor cells and activated an immune response. However, the receptors had one restriction: they could ...

How these EC immune cells can contribute to the brain immunity when implicated by CD36 (an innate immune receptor) is widely unknown. Methods To understand this question, we wanted to investigate how ...

Without these inhibitory receptors, the immune response surges unchecked, leading to heightened inflammation, accelerated T-cell activation, and faster transplant rejection.

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing ...

In order for immune cells to do their job, they need to know against whom they should direct their attack. Research teams at the University of Würzburg have identified new details in this process.