Urothelial CSCs are not isolated ... One possible explanation is that both normal stem cells and CSCs contain lower levels of reactive oxygen species as a result of upregulated free radical ...

Reactive urothelial cells show mild abnormalities that are shared by low-grade neoplastic cells and require considerable screening time from pathologists and cytologists. 9 The presence of ...

Under the WHO/ISUP 1998 system, dysplasia is a flat intraepithelial mucosal proliferation of abnormal urothelial cells that appear more atypical than reactive urothelium, but fall short of the ...

Carcinoma is the word for cancer that starts in epithelial cells, and it is the most common type of cancer. Urothelial carcinoma is also called transitional cell carcinoma because the cells in ...

Urolithiasis: clusters of urothelial cells with reactive changes, finely granular chromatin, conspicuous nucleoli, smooth nuclear contours, and low N/C ratios (i). Magnification: ×600.

Aged urothelial cells also accumulate more damaging reactive oxygen species (ROS) than younger tissues. “ROS are molecules that can harm tissues, and the redox response that normally neutralizes ROS ...

UCs originate in the urothelial cells that line the bladder, as well as the urethra, ureters, renal pelvis, and certain other organs. The cells are also called transitional because they can vary ...

Upper urinary tract urothelial cancer is a rare type of cancer of the lining of the kidney or ureter. It used to be called transitional cell cancer (TCC) of the kidney or ureter. This is because it ...

T24 and UMUC3 cell lines were treated with 1 mM and 5 mM valproate and 1 μM and 5 μM SAHA. Both cell lines showed a reduction in mitotic figures and proliferation under phase contrast (Figure 1).

The research reveals that MAFB and CCAAT/enhancer-binding protein alpha (CEBPA) regulate urothelial cell growth via the Wnt/β-catenin signaling pathway, offering new insights into the genetic ...

Patients with variant histologic types (excluding neuroendocrine carcinoma) could enroll if urothelial carcinoma was predominant; any amount of squamous-cell differentiation was allowed.

MSK’s comprehensive program for patients with upper tract urothelial carcinoma (UTUC ... but the tumor is located in the renal pelvis, arising from the cells lining the kidneys and the ureters. It has ...