Raynaud’s phenomenon is a condition that causes blood vessels in the hands and sometimes the feet to constrict, limiting ...

Scleroderma is a rare disease in which a person's immune system begins to destroy normal, healthy tissues. (This is called an autoimmune disease.) As a result, connective tissue of the skin, lungs, ...

According to a 2023 case report, there is a causal relationship between hypothyroidism and Raynaud phenomenon. Raynaud phenomenon is a condition in which the blood vessels in the extremities ...

Raynaud's disease is a condition that causes parts of your body, like your fingers or toes, to feel cold and numb when you are in cold temperatures or feeling stressed. Raynaud's occurs in 3% to 5 ...

As an orally available inhibitor of endothelin-1, which has been implicated in the pathogenesis of vascular disease in systemic sclerosis (SSc), bosentan is widely used as first-line therapy for ...