The serotonin hypothesis of depression, popular from the 1990s until now, is false, and has been known to be false for a long time, and never was proven to begin with. The norepinephrine ...

Almost as soon as it was floated in 1965 by Harvard psychiatrist Joseph Schildkraut, the serotonin hypothesis of depression—reduced and simplified by pharma marketing to the “chemical ...

A major paper debunking the “serotonin hypothesis” has a lot of people agitated. But leaving more room for nuance in our discussions about mental health is the right idea. Building a more ...

Now, a new study has undermined the aforementioned "serotonin hypothesis" — namely that, as the American Psychiatric Association puts it, "differences in certain chemicals in the brain may ...

In fact, a recent comprehensive analysis of existing studies concluded that there was not strong evidence to support the 'serotonin hypothesis.' In its wake, some in the field have called for a ...

Not everyone is convinced by the findings, though. The serotonin hypothesis, which dates from the 1960s, says that a chemical imbalance in the brain, including low levels of serotonin, also known ...

This theory, which is known as the “serotonin hypothesis,” is based on several data points, including animal research and the effects of antidepressants that are supposed to work by increasing brain ...

Lower serotonin levels in the brain are also thought to be linked to poor orbitofrontal cortex function, which is in turn seen to be present in people with antisocial behavior. Another hypothesis ...

In fact, a recent comprehensive analysis of existing studies concluded that there was not strong evidence to support the "serotonin hypothesis." In its wake, some in the field have called for a ...