leading to obstruction and the consequent buildup of bile salts in the skin. This can cause diffuse itching. When bile flow is impaired or altered, it is known as cholestasis. Other symptoms may ...

LIVMARLI is currently approved for the treatment of pruritus related to ALGS in more ... type 2 patients who have a severe defect in the bile salt export pump (BSEP) protein.

"We are thrilled to see LIVMARLI approved as the first and only medication available in Japan for patients living with pruritus related ... administered, ileal bile acid transporter (IBAT ...