There are many typs of protein modification, which are mostly catalyzed ... by the 26S proteasome and are subsequently targeted for proteolysis or degradation. Monoubiquitinated proteins may ...

Post-translational modification (PTM) is the covalent and generally enzymatic modification of proteins following protein biosynthesis. Proteins are synthesized by ribosomes that translate mRNA into ...

This modification, outlined in a paper published in Neuron, is the mono-methylation (the addition of a methyl group) of the 27th lysine amino acid in the histone H3 protein, also referred to as ...

Lactylation, a recently identified post-translational modification, has emerged as important for immune regulation, tissue repair, cancer cell metabolism, and now, potentially, Alzheimer’s disease. In ...

Protein lactylation is a very recently discovered post-translational modification of protein that involves the addition of a lactyl group to lysine residues. Researchers at the Institute for ...

tuberculosis (Shaban et al., Sci Rep., 2024) with extensive post-translational modifications (Yoshida et al., BBRC., 2023). Recent studies show that IFN-gamma responses to MDP1 are higher in ...