Proteoglycans are ubiquitous molecules that function as critical components of the extracellular matrix. These proteins are composed of glycosaminoglycan chains that are covalently attached to a ...

The distribution of proteoglycans in 21 temporal and two ulnar artery pseudoaneurysms was studied immunohistochemically. A history of trauma was elicited in six cases, and 16 of the lesions were ...

Through multiple interactions of their core proteins and glycosaminoglycans with extracellular matrix proteins, growth factors and chemokines, proteoglycans affect cell signaling, motility ...

The structure of the extracellular matrix differs in composition between tissue types but is essentially made up of collagen fibers, proteoglycans and multiadhesive matrix proteins that are ...

But proteoglycans’ complexity also means ... and the spreading of breast cancer cells on an extracellular matrix. “We learned from these experiments that not only the GAG chains but also ...

In addition to HSPG binding, HB-GAM has similar carbohydrate binding sites in chondroitin sulfate proteoglycans (CSPGs). CSPGs are major inhibitory regulators of plasticity and regeneration in the CNS ...

The NanoBiomechanics Lab focuses on problems in biophysics and biomechanics of extracellular matrix, and more generally ... Osteoarthritis – roles of small leucine-rich proteoglycans and bone ...

The drug is designed to repair damage to the extracellular matrix by mimicking the effect of connective tissue proteins called proteoglycans, and Symic is working through a Phase I/II study to ...

Chondroitin sulfate proteoglycans (CSPGs), commonly obtained ... Furthermore, compositions of other PGs, collagens, and matrix proteins in the skull of sturgeons were similar to that of salmon ...