In living organisms, every protein—a type of biological polymer consisting of hundreds of amino acids—carries out specific ...

Protein folding is the process by which proteins achieve their mature functional (native) tertiary structure, and often begins co-translationally. Protein folding requires chaperones and often ...

The recent findings of Waldo et al. 1 demonstrate that the fusion of the green fluorescent protein (GFP) to insoluble proteins dramatically reduces its folding ability in prokaryotic cells.

And they showed that, through simple and feasible mutation steps ... then why is the folding topology no longer seen today?