(Brenner 1988) The bacterial protease subtilisin uses all of ... in the proper position. As another example, in the enzyme elastase, this pocket is very small, so only proteins with relatively ...

For example, one may imagine that irreversible ... especially as another protease (angiotensin-converting enzyme) acting in the same biochemical pathway is the target of extremely successful ...

Animation showing the transition state of a serine protease—an example of how enzymes are always in motion. Credit: Siyuan Du Until 1926, biochemists were perplexed by reactions that were ...

1 However, bacteria are picky eaters: They cannot take up large molecules such as proteins, which must be broken down into amino acids and smaller peptides by protease enzymes. Given this, scientists ...

is a protease inhibitor "designed to block the activity of the main protease enzyme that the coronavirus needs to replicate." This drug is not a repackaged version of ivermectin. In September 2021 ...