Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing ...

Unexpectedly, the C-terminal sequence YDSL forms a helical turn and both the tyrosine and the C-terminal leucine contact the WW domain. This is unlike other proline-rich peptides complexed to WW ...

The simplest way to decipher the code would be to start with an mRNA molecule of known sequence, use it to direct ... histidine, lysine, proline, and threonine. Remember that previous experiments ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

Src homology 3 (SH3) domain, one of the most abundant protein modules found in eukaryotes, was found to specifically recognize proline-rich sequences adopting polyproline-II helices. Whereas there ...

Protein biosynthesis—the process whereby ... differentially control translation of proline-containing sequences, Nature Communications (2024). DOI: 10.1038/s41467-024-54556-9 Provided by Ludwig ...