Antiphospholipid (aPL) antibodies activate platelet, endothelial cells and monocytes involving p38 MAPK. Tissue factor is an important procoagulant molecule upregulated by aPL antibodies in ...
Antiphospholipid antibodies (present in the serum of patients with APS) are known to induce platelet activation and the production of procoagulants such as von Willebrand factor, thereby ...
This manuscript critically compares the many theories and concepts of anti-phospholipid antibodies ... Our group has reported that chronic platelet activation, not endothelial activation ...
Deficiency of anionic phospholipid exposure and microvesiculation in platelets leads to an inherited bleeding disorder (Scot syndrome). Increased microvesicles have been detected in the circulation in ...