At the time of a platelet symposium in connection with the Fifth International Congress of Hematology considerable variation was reported in the incidence of antibody-induced thrombopenia ...

The fundamental role of platelets in haemostasis and thrombosis ... and statistically analysed by probability analysis. Effects of antibodies and heatmap subtractions were compared using a two ...

Rapid identification of this rare syndrome ... In the 3 index patients, the decision to test for antibodies to platelet factor 4 (PF4) was based on the presence of progressive thrombosis ...

To address this issue, multiplexing platforms have been developed for specificity testing that contain either HLA class I and class II proteins from platelets, or antigens from transformed cell ...

Moreover, they show that the antibody carries out its mission by triggering a particular biochemical pathway in the platelets. The new study is published in the September 7 issue of the journal Cell.

In this study, scientists from the Antibodies in Therapy and Pathology Unit (Institut Pasteur/Inserm U1222) revealed that platelets, whose best-known function is to stop bleeding when a blood ...

In this new work, the team armed platelet-derived microparticles with an IL-1β blocking antibody (the same one tested in the clinical trials) and tested it in a mouse model. Drug concentration in ...

NEW ORLEANS — An antibody treatment developed by the Belgian drugmaker Argenx raised platelet counts and stopped bleeding episodes in patients with a rare autoimmune disorder that causes the ...

Belgian drugmaker Argenx said Tuesday that its antibody medicine failed to achieve the goals of a late-stage study for a platelet-destroying autoimmune disorder — a setback in the company’s ...

The new study, in which an antibody is used to limit the outflow of clot-forming platelets from the bone marrow in baboons, appears in the June 23 Science Translational Medicine. Preventing blood ...

Patients suspected of having thrombocytopenia, or low blood platelet count often associated with bleeding, can be tested for a special type of antibody to see if it is related to medications.