Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive form of blood cancer that primarily affects older adults. It is characterized by the proliferation of precursors of ...
Immunotherapies use the body's own immune system to fight cancer cells. Plasmacytoid dendritic cells (pDCs), which are activated by Imiquimod via TLR7/8, play an important role in this process. The ...
As compared to pancreatic cancer subtype classifier (PurIST ... macrophage activity, and plasmacytoid dendritic cell levels, all of which can lead to reduced tumor immunogenicity.