Plasma cell differentiation required IRF4 as well ... the generation of plasma cells both from GC and memory B cells; and CSR. Finally, our results have implications for the function of IRF4 ...

While B cell differentiation requires cell division ... DNA methylation is remodeled in germinal center B cells, memory B cells and plasma cells 12,13,14. However, the breadth, timing and function ...

Scientists have clarified the mechanism for inducing germinal-center B cells' differentiation into memory B cells, immune cells that remember antigens, at the molecular level. A group of ...

It is associated with the development of antibodies, memory B cells ... (a short-lived differentiation stage between a post germinal center B-cell and a mature plasma cell), the subsequent ...

Thanks to the memory capabilities of our immune cells, our body knows how to fight pathogens better the second, third, and fourth times we encounter them. Immune memory also makes vaccination possible ...

For example, memory B cells are a type of white blood cell that are created in lymph ... by the same virus or bacteria. In contrast, plasma cells are much more numerous and help during an initial ...

Maria Curotto de Lafaille’s lab was trying to make human plasma ... memory B cells, which Koenig calls MBC2s in his paper. More than 80% of the connections the researchers could make were to the ...

The study identified 12 different cell subsets, with more differentiated states (memory B cells and plasma cells) being highly enriched in the tumors relative to adjacent normal tissue.

Some of the B cell memory is cross-reactive against past coronavirus infections. Strangely, however, the anti-RBD IgG1 response is proportional to the IgM+ memory cells, since the latter do not ...

Co-authors with Ballesteros-Tato in the study, “Interferon-γ production by Tfh cells is required for CXCR3+ pre-memory B cell differentiation and subsequent lung-resident memory B cell responses,” are ...

Evidence from transcriptional and epigenetic profiling shows that the cells in this subset differ from all previously described memory B cell subsets ... vaccines induce the formation of long-lived ...

They involve numerous types of cells and proteins, performing precise step-by-step processes. And of course, we don’t know all of them yet. For example, memory B cells are a type of white blood cell ...