A study in Reproductive and Developmental Medicine links elevated levels of the KLF12 protein to impaired placental development, a major cause of unexplained miscarriages affecting 15% of pregnancies.

The processes involved in placental development are highly regulated to ensure normal growth of the developing fetal tissues and the maintenance of a healthy pregnancy. A unique function of the ...

The team then tested how the enzyme ACE2 affects the development of the placenta, using gene-editing to create placental organoids with different versions of the ACE2 gene. "We wanted to ...

A new study highlights the placenta’s role in neuropsychiatric development, showing that DNA methylation influences gene ...

An international team led by UPV/EHU and Biobizkaia reveals the relationship between placental DNA methylation and certain ...

The inner cell mass gives rise to the fetus, while the surrounding trophectoderm transforms into the placenta. After implantation, the trophectoderm starts reshaping the endometrium. A layer of ...

What's more, environmental factors that disrupt these signals in prospective fathers increase the risk of adverse health in offspring, through altering placental development. This implies that in ...

“It's a really exciting time for placenta development now that we have advances in things like single-cell RNA sequencing, and there are a lot of datasets in the field that people can integrate with ...

Discover how the placenta plays a crucial role in schizophrenia risk, influencing brain development and genetic ...

An international team, led by the Immunogenetics Research Laboratory (IRLab) at the University of the Basque Country (UPV/EHU ...