Researchers at Baylor College of Medicine have discovered that certain p53 mutants hijack the DNA replication machinery ...

The gene p53 acts as a tumor suppressor and is often called the guardian of the genome. This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading to ...

Figure 8: Regulation of ALDH3A1 and NECTIN4 by p53. Researchers Jessica J. Miciak, Lucy Petrova, Rhythm Sajwan, Aditya Pandya, Mikayla Deckard, Andrew J. Munoz, and Fred Bunz from the Sidney Kimmel ...

These particles don't just sit harmlessly in the body; they trigger chronic inflammation, oxidative stress, and DNA damage.

In a recent perspective published in the journal Cell Death and Differentiation, researchers in France, Germany, and Sweden discussed the unique mutational spectrum of the transformation-related ...

A rising wave of tumor-agnostic therapies were one of ESMO’s themes, highlighted during the opening press conference by Toni ...

Sir2, an enzyme belonging to sirtuins, has been shown to be involved in the deacetylation of proteins. Researchers from the ...

The MarketWatch News Department was not involved in the creation of this content.-- FMC-376 demonstrated robust anti-tumor activity across preclinical models and led to deeper inh ...

An exciting new study from an international team of scientists has shed some light on exactly why elephants, one of the biggest animals on the planet, paradoxically experience unusually low rates of ...

(Boston)—For more than 100 years, it has been believed that sunlight and vitamin D deficiency were associated with the risk for many deadly cancers including colorectal, prostate and breast. But some ...