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Malaria remains a persistent public health burden, with Plasmodium falciparum causing the most dangerous form of malaria and ...
vivax malaria (10 patients) or P. falciparum malaria (11). The primary end point was the parasite clearance time. The primary objective of this phase 2, open-label study was to assess the initial ...
Malaria is most commonly transmitted through the bites of female Anopheles mosquitoes infected with P. falciparum. The latest world malaria report states that in 2022, there were an estimated 249 ...
There are available treatments, but drug resistance is an ongoing problem. During a malaria infection, the P. falciparum parasite injects 10% of its proteins into host red blood cells, remodelling ...
Why do you think this is the case? The P. falciparum RAP01 and RAP21 proteins that we studied belong to the "RNA-binding domain abundant in Apicomplexans" (RAP) protein family. Because this ...
A significantly higher frequency of P. falciparum–specific polyfunctional CD4+ and Vδ2+ γδ T cells were observed among participants who received GA2 than among those who received GA1 ...
A long-standing mystery in the field has revolved around a very few locations in the P. falciparum genome where there are 'spikes' of mutations -- far more than anywhere else. Researchers have ...