The number of replication origin sequences in the genome does not change during the lifespan of an organism, but the number of active origins does vary according to the developmental stage. In the ...

As previously mentioned, the location at which a DNA strand begins to unwind into two separate single strands is known as the origin of replication. As shown in Figure 1, when the double helix ...

In eukaryotes, DNA replication initiates at many replication origins that are distributed along the length of each chromosome arm. At each origin, two replication forks are established that travel in ...