with a distance of 0.9 Å between the two C4 atoms in the nicotinamide ring. With residues in region 3 in overlap, a rotation of 10.6° is required to bring region 2 into superposition ...
In a retrospective cohort study, nicotinamide exposure showed no increased risk for MACE. Prior MACE history, however, was strongly associated with subsequent MACE. To address recent safety ...