Researchers have mapped how "histone bivalency" acts as a molecular clock for brain development. By holding genes in a poised state, this mechanism ensures neurons mature only after completing ...

The brain is the most complex organ in the human body. Different parts of the brain perform a variety of functions, all of ...

In a new study from Karolinska Institutet, published in Nature Neuroscience, researchers have identified the neurogenic progenitor that gives rise to dopaminergic neurons, the primary neurons affected ...

Duke University Medical Center-led research has identified a human-specific DNA enhancer that regulates neural progenitor proliferation and cortical size. Small genetic changes in HARE5 amplify a key ...

ALS is a heterogeneous disease. While 10-15% of cases are linked to inherited mutations, nearly 85% are sporadic.

To better model how neurons fire and interact with glia, some scientists place the cells into a brain or grow them in an organoid. Others have produced little spheres of human neural tissue by ...

Study reveals how proteins direct nerve cell precursors to turn into specialized neurons. Brain development is a highly orchestrated process involving numerous parallel and sequential steps. Many of ...

Leuven, 7 August 2024—The mechanisms underlying intellectual disabilities or autism remain largely unknown. Researchers in the labs of Prof. Pierre Vanderhaeghen and Prof. Vincent Bonin at the VIB-KU ...

A baby's neuronal development can be compromised by infections in utero Source: Peter Oslanec/Unsplash It goes without saying that the health of a pregnant mother and the conditions inside the womb ...