Most epithelial tissues contain self-renewing stem cells that mature into downstream progenies with increasingly limited differentiation potential. It is not surprising that cancers arising from ...

A neoplasm is an abnormal growth of cells, also known as a tumor. Neoplastic diseases are conditions that cause tumor growth. Growth can be either benign (noncancerous) or malignant (cancerous).

These rogue cells, which are otherwise referred to as neoplastic cells, cannot be controlled in the way that normal cells can because they do not die when they should and they divide more quickly.

Although neoplasms often comprise more than one cell type, their initial development and growth is dependent on a population of one single type of neoplastic cells descended form one progenitor.

While autologous stem cell transplantation is a potentially curative option for relapsed or refractory Hodgkin lymphoma, certain characteristics in the transplant product may carry a risk of ...

A blastic plasmacytoid dendritic-cell neoplasm is a rare tumor with very aggressive clinical behavior and no established treatment. 1 Available treatment options include aggressive multiagent ...

In this study, a hematopoietic stem cell-transplanted humanized mouse model infected with a gene-modified HIV-1 was used to reveal multiple characteristics of HIV-1-producing cells in vivo.

Using iPS cells generated from a patient with a myeloid neoplasm caused by a rare chromosomal rearrangement between the MECOM and MYC genes, a team of researchers led by Associate Professor ...