Chandran said he hopes his research will lead to the development of drug that uses NPC1 to stop an Ebola infection. "What we're trying to do is develop small molecule therapy that would ...

Cyclo Therapeutics has been granted Orphan Drug Designation for Trappsol® Cyclo™ to treat NPC1 in the U.S. and EU, along with Fast Track and Rare Pediatric Disease Designations in the U.S.

NPC1 mRNA was measured by RT-qPCR in lean and obese individuals, paired samples of subcutaneous (sc) and omental (om) WAT, before and after weight loss, in isolated adipocytes and intact adipose ...

NPC1's amino acid sequence homology to PATCHED, human HMG-CoA reductase and SCAP. Credit: Reprinted with permission from AAAS / Carstea et al., Science 277:228, 1997." />NPC1's amino acid sequence ...

In this case, the team were investigating the role two proteins, NPC1 and NPC2, play in transporting low-density lipoprotein (LDL) cholesterol, often referred to as “bad” cholesterol, into our ...

(RTTNews) - Cyclo Therapeutics, Inc. (CYTH) on Friday announced promising preliminary data from its ongoing Phase 3 TransportNPC study, evaluating Trappsol Cyclo for the treatment of Niemann-Pick ...

Berry-Kravis, the Andrews girls' specialist in Chicago, says there's about a 1 in 100,000 chance of a baby being born with NPC1. Even with that many newborns screened, there's a chance that the ...

Cyclo Therapeutics Presents Encouraging Preliminary Safety Data from Ongoing Pivotal Phase 3 Study and Substudy for the Treatment of Niemann-Pick Disease Type C1 (NPC1) Business Wire Thu, Sep 5 ...