The first class of well differentiated liposarcoma includes lipoma-like, sclerosing, inflammatory and spindle ... of myxoid liposarcoma of which a proportion of cases progresses to round cell ...

The patient was originally diagnosed with myxoid liposarcoma of the right anterior ... phase contrast microscopy revealed spindle cell morphology in monolayer culture (Figure 1b).

Letetresgene autoleucel (lete-cel) showed a 42% response rate in a phase 2 trial for synovial sarcoma and myxoid/round cell liposarcoma. The trial included 64 patients, with 41% response in synovial ...

After you get a diagnosis of liposarcoma, a type of cancer that starts in fat cells, your doctor will discuss ... Some types of liposarcoma, such as myxoid liposarcoma, respond better to ...

The clinical trial was an international study that treated a total of 52 people who had been diagnosed with synovial sarcoma and myxoid/round cell liposarcoma (MRCLS), another type of soft tissue ...

for lete-cel for the treatment of advanced or metastatic synovial sarcoma and myxoid/round cell liposarcoma (MRCLS) by the end of 2025. Data from the Phase II IGNYTE-ESO trial (NCT03967223 ...

Interim analysis of pivotal IGNYTE-ESO trial demonstrates 40% response rate in people with synovial sarcoma or myxoid/ round cell liposarcoma Company will lay out plans for its cell therapy ...

The Company previously received breakthrough therapy designation for lete-cel for the treatment of synovial sarcoma in 2016. In the Phase II analysis, 27/64 (42%) people with synovial sarcoma or ...

A total of 44 patients with cytogenetically confirmed synovial sarcoma, and 8 patients with myxoid round cell liposarcoma, were enrolled and received afamitresgene-autoleucel. The primary outcome ...