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Sino Biological is dedicated to creating multi-pass transmembrane protein products and has established three platforms to supply vital raw materials for early-stage medication development.
Sino Biological has created a VLP protein platform based on the HEK293 expression system for producing full-length multi-pass transmembrane proteins (e.g. GPRC5D).
Transmembrane proteins, especially those with multiple transmembrane domains, present significant challenges for antibody drug design due to their complex structures. A deep understanding of the 3D ...
Determining the structure of transmembrane proteins is difficult because portions of transmembrane proteins must pass though the membrane's interior ... and assemble into stable multi-protein ...
By swapping hydrophobic amino acids for structurally similar hydrophilic ones, the researchers transform hydrophobic transmembrane receptors into water-soluble proteins that don’t need ...
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