Dozens of intranasally delivered vaccines targeting SARS-CoV-2 are in development. Could they pave the way for widespread nasal vaccination in the future? A series of rodent experiments showed that ...

However, while intramuscular vaccines produce robust circulating antibody and systemic memory cell responses, these poorly protect the mucosal barriers, such as the respiratory tract. “An improved ...

The possibility of developing oral vaccines against non-mucosal pathogens is supported by studies with Japanese encephalitis and hepatitis B, which are transmitted by mosquito- and blood-borne ...

Integrating basic and clinical research is key to the development of safe and effective mucosal vaccines taken orally or nasally, says Hiroshi Kiyono of the Institute of Medical Science ...

Results indicate that the vaccine was safe and well tolerated while eliciting robust systemic and mucosal immune responses in adults aged 55 to 80 years. Norovirus infections cause approximately ...

So we need to consider a vaccine strategy that will provide longer-term immunity. A new kid on the block – mucosal vaccines – could offer promise on this front. Mucosal vaccines are delivered in your ...

Orexo announces positive data for powder-based intranasal vaccine formulated with the AmorphOX technology: Uppsala, Sweden Saturday, April 12, 2025, 13:00 Hrs [IST] Orexo AB (publ ...

Strategies to optimize the benefits of maternal immunization include novel vaccine formulations and mucosal route of delivery. One of the key determinants of a successful pregnancy is mutual fetal ...

Ethris has partnered with contract development and manufacturing organisation Lonza for the development of room-temperature stable mRNA vaccine candidates targeting respiratory conditions.

In 10 years' time, we should not be starting a vaccine project without knowing the structure of the relevant antigens. The third bridge: harnessing T-cell and mucosal immunity ...