A major scientific advance in protein modeling developed by Microsoft Research AI for Science, has been published in Science.

More information: Florian Seufert et al, Generic residue numbering of the GAIN domain of adhesion GPCRs, Nature Communications (2025). DOI: 10.1038/s41467-024-55466-6 Provided by Leipzig University ...

WIKIMEDIA, CHAOS Using the CRISPR/Cas9 genome-editing system to mutate the gene regions encoding particular protein domains could result in a new and more efficient method to screen for druggable ...

A study published in mBio details the vulnerability of coronaviruses to inhibitors of a small protein domain called Mac1, or ...

New numbering system facilitates comparability of protein domains. ScienceDaily . Retrieved June 11, 2025 from www.sciencedaily.com / releases / 2025 / 01 / 250128123928.htm ...

To create the Human Domainome 1 library, the team methodically mutated each amino acid to all 19 alternatives at every position, generating more than 500,000 variants across 522 protein domains. “The ...

Large proteins with multiple domains may have more stable conformations than previously believed Date: August 9, 2016 ... They discovered that one-half of the protein, called a domain, ...

More specifically, ... FIH as an asparaginyl hydroxylase enzyme and for the first time demonstrate enzymatic activity for a mammalian JmjC-domain protein.