Some of this calcium is taken up by mitochondria, where it is used ... a mouse model in which MICU1 is specifically missing in skeletal muscles. They also harvested muscle fibroblasts from ...

Study: Mitochondrial calcium uptake declines during aging and is directly activated by oleuropein to boost energy metabolism and skeletal muscle performance. Image Credit: ART-ur/Shutterstock.com ...

Lack of the protein mitochondrial calcium uptake1 (MICU1 ... model whose MICU1 gene was deleted in the muscles. Loss of MICU1 in skeletal muscle fibers leads to less contractile force, increased ...

Although this phenomenon has long been identified and has been suggested that weight loss may alter skeletal muscle mitochondrial respiration, the mechanisms are not fully understood and direct ...

Explore the impact of OPA1 deletion in skeletal muscle on mitochondrial–endoplasmic reticulum (ER) tethering and the electron microscopy techniques used to investigate these mitochondrial–ER contact ...

Chemotherapy may lead to mitochondrial dysfunction in skeletal muscle. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2018 / 10 / 181004131819.htm ...

Study uncovers a polyphenol's mechanism in enhancing mitochondrial calcium uptake and muscle ... decline and chronic diseases. In skeletal muscle, mtCa²⁺ uptake, regulated by the MCU, plays ...

In April 2023, Professor Katsuhiko Funai at University of Utah published a study in Life Metabolism entitled "Weight loss increases skeletal muscle mitochondrial energy efficiency in obese mice." ...