Microsatellite instability and loss of heterozygosity has been implicated in ovarian carcinogenesis. The reported frequency of microsatellite instability in human ovarian cancer varies significantly ...

Subjects who provided tissue samples were 322 consecutive women with primary epithelial ovarian cancer who had undergone initial surgery at The University of Texas MD Anderson Cancer Center between ...

MADISON, Wis.--(BUSINESS WIRE)--Researchers from Johns Hopkins University have shown that a new panel of long mononucleotide repeats (LMR) might offer advantages over traditional microsatellite ...

Genomes of tumors that are deficient in DNA mismatch repair (dMMR) have high microsatellite instability (MSI-H) and harbor hundreds to thousands of somatic mutations that encode potential neoantigens.

Researchers from Johns Hopkins University have shown that a new panel of long mononucleotide repeats (LMR) might offer advantages over traditional microsatellite instability (MSI) detection methods in ...

CURE spoke with Scott Paulson, M.D., medical oncologist with Texas Oncology, an affiliate of The US Oncology Network, to break down exactly what MSI-H status is, and the effects it may have on certain ...

Microsatellite instability is a genetic condition that could be difficult to understand. We broke it down to explain how it works. Microsatellite instability (MSI) is a signature associated with the ...

Nimbus Therapeutics, LLC ("Nimbus Therapeutics" or "Nimbus"), a biotechnology company that designs and develops breakthrough ...

MSI has rapidly advanced as an important pan tumor biomarker associated with response to immune checkpoint inhibitors and the drive towards universal tumor testing. Join Session 3 to learn more about ...

TABOSUN® (ipilimumab N01 injection) has been approved in combination with TYVYT® (sintilimab injection) for the neoadjuvant treatment of patients with stage IIB-III resectable microsatellite ...

Promega Corporation, a manufacturer of innovative solutions for molecular diagnostics, clinical research, life sciences, and human identification will host its second session in A Microsatellite ...