Neuroimaging showed gliosis and atrophy of the right hippocampus, characteristic of mesial temporal sclerosis (Figure 1). Patients classically present with complex partial seizures lasting one to two ...

Copyright (c) 2024 Samir Alsalek, Alexander S. Himstead, Scott Self, Gianna M. Fote, Sumeet Vadera, Edwin S. Monuki, Mari Perez-Rosendahl, William H. Yong This work ...

We emphasize demographic, clinical, genetic and neuroimaging features, and treatment of this type of epilepsy. ≈30% have positive family history of febrile seizures or epilepsy ≈15% have ...

The researchers in this study asked whether infections with human herpesvirus 6B (HHV-6B) are associated with a common type of epilepsy called mesial temporal lobe epilepsy (MTLE). Patients with ...

refractory mesial temporal lobe epilepsy, amyotrophic lateral sclerosis uniQure Forward-Looking Statements This press release contains forward-looking statements. All statements other than ...

LEXINGTON, Mass. and AMSTERDAM, May 29, 2025 (GLOBE NEWSWIRE) -- uniQure N.V. (NASDAQ: QURE), a leading gene therapy company advancing transformative therapies for patients with severe medical ...

Researchers from The Brigham and Women's Hospital presented data from a study that aimed to evaluate the role of somatic variants in drug-resistant mesial temporal lobe epilepsy (MTLE). High-coverage ...

SLC12A2) and exporter KCC2 (K-Cl cotransporter 2, SLC12A5) is involved in neurodevelopmental and neurologic conditions, including mesial temporal lobe epilepsy (MTLE), among others, leading to an ...

"These early results from the first trial participant are very encouraging and support our belief that AMT-260 has the potential to be a valuable treatment alternative for people living with ...

Approximately 80% of all temporal lobe epilepsy cases are mesial, which involves the medial (or internal) structures of the brain. The majority of MTLE cases are refractory to anti-seizure ...