Serious and life-threatening risks from use of MS Contin: Addiction ... during initiation or following dose increases. Accidental exposure may cause fatal overdose (esp. in children).

MS Contin) and oxycodone (OxyContin). These products vary in regard to their active ingredient, dosage form, mechanism of drug release, dosing frequency, pharmacokinetic profile, and cost.

Objective: To compare pain control, patient preference and tolerability for two extended-release formulations of morphine sulfate, Kadian ® capsules (administered once daily) and MS Contin ...