Unbiased, high-throughput assays for detecting and quantifying DNA double-stranded breaks (DSBs ... Here we describe a linear amplification–mediated high-throughput genome-wide sequencing ...

Double-stranded DNA consists of two polynucleotides that ... whereas most eukaryotes have one or more linear chromosomes, which often appear as X-shaped structures . At different times during ...

What is the fate of linear mtDNA? Double-strand breaks (DSBs ... bias for operation in the 5' to 3' direction of single-stranded DNA then begins to digest one strand. The key insight the authors ...

Double-stranded linear DNA HBV genomes can integrate into the hepatocyte genome at sites of DNA breaks. ER denotes endoplasmic reticulum, and SMC5/6 structural maintenance of chromosomes 5 and 6.

GenScript USA Inc., a global leader in life science research tools and services, recently announced the launch of the GenWand™ Double-Stranded ... closed-end linear DNA to help enhance dsDNA ...

The bonded molecules formed a linear double-stranded DNA structure with a separate and functional side group. The researchers then created a trigger molecule that attached to the side group and ...

A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

Previously, lengths of double-stranded DNA have been used for nanoscale constructions ... Three primary rules were established. First, linear folding paths were found to be preferable to branched ...

either in sequence-perfect clonal DNA format or a faster, sequence-verified linear double-stranded DNA fragment format. Sequences can include extreme GC content, tandem repeats, and secondary ...