The team, led by Professor Koji Nishida, used induced pluripotent stem cells (iPS) to perform corneal transplants, marking a significant advancement in treatment. Limbal stem-cell deficiency is a ...

Once diagnosed, treatment options vary based on the severity of the condition and may include limbal stem cell transplantation or the use of alternative stem cell sources, such as oral or nasal ...

The study focused on four patients with limbal stem-cell deficiency (LSCD), a condition that leads to blindness due to corneal scarring. These patients received corneal cell transplants derived ...

Patients with limbal deficiency may benefit from limbal stem cell transplantation to alleviate ... herald a paradigm shift in management and treatment of OSD. Previously, most patients with ...

If the cornea is badly damaged, limbal stem cells can taken from the patient, grown in the lab and then transplanted back on to the patient’s damaged eye, or eyes, in order to restore sight.

and reduced need for immunosuppressive therapy. Since these tissues are not corneal epithelium and do not possess innate limbal stem cells, it would be interesting to perform longitudinal studies ...