Examples of some such functions ... There are six main categories of enzymes: oxidoreductases, transferases, hydrolases, lyases, isomerases and ligases – each classified by their mechanism ...

These small drug compounds destabilise proteins by bringing them into proximity with enzymes called E3 ubiquitin ligases that cause them to be broken down. BMS pays $200m to expand Evotec alliance ...

New research published today, in Nature, describes a new family of enzymes (ligases) which can assemble the key chemical ... Amide bonds are very important in nature. For example, the protein ...

We have examined the interaction of eukaryotic ligases with DNA using virus-encoded enzymes as models. Vaccinia virus DNA ligase and Chlorella virus DNA ligase each form a discrete complex with a ...