Intravenous bolus fluorouracil plus leucovorin is the standard adjuvant treatment for colon cancer. The oral fluoropyrimidine capecitabine is an established alternative to bolus fluorouracil plus ...

Abbreviations: Xelox, capecitabine and oxaliplatin; FUOX, fluorouracil plus capecitabine; CI, continuous infusion; FOLFOX-4, oxaliplatin plus infusional FU and leucovorin; mFOLFOX-6, modified ...

He calculates that in the 12-week treatment schedule, the total cost of capecitabine is $7045, while the cost of FU is only $30 to $52 (depending on dosing schedule) and leucovorin, when it is ...

5-FU plus leucovorin (5-FU/LV) as first-line treatment for metastatic colorectal cancer. PATIENTS AND METHODS: We prospectively randomized 602 patients to treatment with capecitabine 1,250 mg/m 2 ...

and maintenance in this group with capecitabine or 5-fluorouracil-leucovorin alone may be sufficient. "Where do we go from here?" he said. "If we are reading a history book on maintenance ...

Leucovorin is a folic acid analog, prescribed for reducing the toxic effects of methotrexate. The serum concentration of the active metabolites of Leucovorin can be reduced when Leucovorin is used ...

Two oral treatments, capecitabine (Xeloda ®, Roche) and UFT/LV (tegafur with uracil in combination with leucovorin, marketed as Uftoral ®, Bristol-Myers Squibb), are licensed for use in the UK.

From November 2020 to April 2024, the CASSANDRA PACT-21 trial randomized 260 adults with stage I-III pancreatic cancer at 17 ...