The diagnosis of leukemia relies upon a multiparametric approach involving a number of different pathology disciplines. Molecular methods are increasingly employed to help refine diagnosis ...

In addition to exporting materials out of the nucleus, the protein, called Exportin-1 (also called Xpo1 or Crm1), seems to play a role in promoting gene transcription, the process that creates RNA ...

"Although all experts agree that chromosomal chaos is the cause of the poor therapeutic response of these leukemia cells, no one knows exactly which molecular changes contribute to disease ...