When organisms encounter problems—what scientists call "replication stress ... guanine bases (represented by G in the DNA ...

Chemla's lab team looked at the structure-function relationship in the helicase UvrD, a protein, found in the bacterium E. coli, that separates strands of DNA in need of repair by unwinding and ...

We employ fully reconstituted yeast and human DNA replication systems to investigate the structure and biochemical mechanism of the eukaryotic replication machinery. A particular focus of the lab is ...

Watson and Crick's discovery of DNA structure in 1953 revealed a possible mechanism for DNA replication. So why didn't Meselson and Stahl finally explain this mechanism until 1958 ...

Z-DNA has a left-handed double helix structure. It is said to be found during the start of a gene. DNA replication occurs in the S phase of the cell cycle. DNA replication is the process where ...

Revising DNA structure and replication? This Higher Human Biology guide is packed with information to help. Higher Human Biology - Structure and replication of DNA. revision-guideHigher Human ...

Researchers discovered that HSV-1 (herpes simplex virus) actively reshapes the 3D layout of human DNA within hours of ...

Researchers at IRB Barcelona publish the structure of the RepB protein bound to DNA, a key protein in triggering the replication of ... and Molecular Machines lab at IRB Barcelona and professor ...

“Our lab is generally interested in discovering and characterizing ... this gene increases the sensitivity of cells to various agents that damage DNA particularly during replication.” “Inter-strand ...

These “escapee” cells exhibited DNA replication deficits, accumulated DNA lesions, and mounted a stress response that depended on the ataxia telangiectasia and RAD3-related (ATR) kinase. We further ...