This approach, which has already enabled the spleen to perform a liver-like function in mouse models, could present an alternative to organ transplantation or engineering. [Lei Dong, Nanjing ...

We can survive without a spleen, but people who need a liver transplant can face a long wait Repurposing the spleens of mice helps them to survive liver damage. If the approach works in people, it ...

Then, they implant mouse, rat and human liver cells into the remodelled spleen in mice, observing in months that these cells not only survive from immune rejection and grow into liver-like ...

Liver, kidney and spleen were homogenized in buffer containing 50 mM Tris pH 7.5, 5 mM MgCl 2, 1 mM dithiothreitol and 250 mM sucrose and centrifuged for 10 min at 14,000g at 4 °C.

A team from Nanjing University and University of Macau has transformed the spleen to perform liver functions in mice, without transplanting cells or tissue from another body. The research is ...

How do you study-and try to cure in the laboratory-an infection that only humans can get? A team led by Salk Institute researchers does it by generating a mouse with an almost completely human liver.

The device produces detailed, computerized, 3-D images that show how your liver and spleen are functioning. (Areas where the tracers collect in low amounts show up as dark spots.

Spleen stiffness measurement (SSM) demonstrated strong predictive accuracy for liver decompensation in patients with compensated advanced chronic liver disease (cACLD), with an optimal cutoff of ...

More information: Xue‐Jiao Tian et al, Regeneration of Thyroid Glands in the Spleen Restores Homeostasis in Thyroidectomy Mice, Advanced Science (2023). DOI: 10.1002/advs.202305913 Journal ...