Type 1 interferon deficiency: Biomarker of patients at risk of severe COVID-19. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2020 / 07 / 200717101015.htm ...

Figure 1: Histological lesions and immunohistochemical and ultrastructural detection of SCV in lungs of experimentally infected macaques. Figure 2: Antiviral activity of pegylated IFN-α against ...

At baseline, the majority of patients (62.9%) were considered IFN high, and 30.2% were considered IFN low. The remaining 6.8% were considered borderline. Of the initial 205 patients, 142 patients ...

Levels of circulating Type 1 IFN could even characterize each stage of disease, with the lowest levels observed in the most severe patients. These results suggest that in SARS-CoV-2 infection, ...

For the first time in nonhuman primates, Emory University researchers studied how modulating the signaling of type 1 Interferon (IFN-I) impacts SARS-CoV-2 viral replication and disease progression.

Young patients with type 1 diabetes assigned to low doses of human recombinant interferon-alpha treatment maintained more beta-cell function one year following study enrollment when compared with ...

The type III 113 (λ) interferons were found the be the least potent seen in Figure 2 below. Figure 2: Sensitivity of SARS-CoV-2 variants to diverse Interferons. Interferon Resistance of Emerging ...

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Accordingly, patients with monogenic defects along the interleukin-12–interferon-γ axis are susceptible to disseminated coccidioidomycosis. 2 On the other hand, type 2 immune responses may be ...

There are three basic forms of interferon. These are alpha and beta, also known as type 1, while gamma is known as type 2. Each form of interferon has different effects on the body.

Levels of circulating Type 1 IFN could even characterize each stage of disease, with the lowest levels observed in the most severe patients. These results suggest that in SARS-CoV-2 infection, ...