Binding of PLSCR1 to TLR9 is necessary for type 1 IFN production. When different PLSCR1 fragments were overexpressed in GEN2.2 cells, the scramblase domain alone (unable to bind to TLR9 ...

A 56-year-old man underwent resection of a 2.1 × 1.0 × 0.6 cm lesion from his ... One month later he began therapy with interferon α-2b, receiving 37 million units daily intravenously on ...

Memorial Sloan Kettering Cancer Center investigators report that T cell interferon-γ (IFNγ) orchestrates a ...

The annualized relapse rate was lower with ocrelizumab than with interferon beta-1a in trial 1 (0.16 vs ... for an infusion-related reaction is a type 2 hypersensitivity reaction, in which ...