Insulin gene mutations can cause permanent neonatal diabetes, a rare form of diabetes that affects very young children. This is the first time that an insulin mutation has been connected to severe ...

Insulin gene mutations can cause permanent neonatal diabetes, a rare form of diabetes that affects very young children. This is the first time that an insulin mutation has been connected to severe ...

Mutations in the gene encoding Kir6.2 probably cause decreased secretion of insulin from beta cells by conferring reduced sensitivity to ATP, which is predicted to result in gain of channel function.

We assessed glycemic control in 49 consecutive patients with Kir6.2 mutations who received appropriate doses of sulfonylureas and, in smaller subgroups, investigated the insulin secretory ...

Single gene mutation found to cause insulin sensitivity. By Loren Grush Fox News. Published September 13, 2012 9:08am EDT | Updated October 27, 2015 1:57am EDT. Facebook ...

Researchers have identified a missense mutation in a gene responsible for the regulation of insulin secretion that is likely associated with two distinct phenotypes, including multiple insulin ...

Low birth weight and fetal thinness have been associated with non-insulin dependent diabetes mellitus (NIDDM) and insulin resistance in childhood and adulthood1,2,3,4,5,6. It has been proposed ...

By Nancy Lapid (Reuters) -Insulin-producing human pancreas cells can be manufactured with 3D printers, researchers reported at the International Transplant Congress underway in Lo ...

Analysis of human PC1/3 obesity-associated mutations showed increased binding to BiP and prolonged ... PC1/3 (kind gift from Dr Iris Lindberg), insulin #3B7 (kind gift from Dr John Hutton ...

Mutations in the insulin gene can cause permanent neonatal diabetes, an unusual form of diabetes that affects very young children and results in lifelong dependence on insulin injections, report ...