blood sugar levels and sensitivity to the hormone insulin, which is involved in blood sugar control. People with the mutation also had higher levels of a compound called low-density lipoprotein ...

Patients show rapid catch-up growth after insulin treatment. The reason that some Kir6.2 mutations give rise to transient neonatal diabetes is unknown, but possible explanations include a reduced ...

we have seen that the majority of older and obese patients develop insulin resistance and three men and eight women suffered ...

Frequent blood donors may experience subtle genetic changes that could lower their risk of developing blood cancers, ...

to cause insulin resistance; genetic heterogeneity, i.e., the ability of mutations in different genes to bring about the same metabolic trait (for example, fasting hyperinsulinemia); and polygenic ...

While genetics studies have identified mutations that increase the risk of developing type ... Previously, Altindis and his team made a surprising discovery and showed that viruses have insulin-like ...

Type II (non-insulin dependent) diabetes is a complex ... play important roles in development of type II diabetes . Thus, mutations or polymorphisms that cause only modest deficits in gene/protein ...

Neonatal diabetes can result from mutations in either Kir6.2 or SUR1 subunits of the pancreatic potassium ATP channel, which disrupt insulin release. Sulfonylureas close these channels and restore ...

If glucose reaches the threshold of the enzyme, the pancreas releases its insulin. MODY variants (=mutations) in GCK raise this threshold level. In early stages of HNF1A and HNF4A, fasting glucose can ...