Initiator proteins are key components of the DNA replication machinery that determine where initiation will occur. In the past few years, due to a greatly improved understanding of what viral ...

These include a set of initiator proteins to begin each new replication fork at a replication origin, an RNAseH enzyme to remove the RNA primers from the Okazaki fragments, and a DNA ligase to ...

“These other proteins can help add layers of complexity, such as assisting with helicase loading or inactivating the initiator after replication has begun.The open rings also probably allow DNA ...

The structure of a protein key to the replication of antibiotic-resistance-conferring plasmids has been described in a new study. ... Ruiz-Masó JA, Amodio J, et al. Structures of pMV158 replication ...

How protein machinery binds and wraps DNA to start replication Date: March 6, 2012 Source: DOE/Brookhaven National Laboratory Summary: Scientists have deciphered molecular-level details of the ...

XPG binds bubble DNA and breaks the stacking of unpaired bases, bending DNA severely. Only then does XPG recruit and load into place other proteins that finally smooth things out.

A protein structure reveals how replication of DNA coding for antibiotic resistance is initiated Peer-Reviewed Publication. Institute for Research in Biomedicine (IRB Barcelona) ...

A protein that prepares DNA for replication also prevents the replication process from running out of control, according to a new study by Weill Cornell Medicine researchers. The work, published ...

In all living organisms, DNA replication is essential to ensure the genetic fidelity of the next generation. However, bacteria can also transfer genetic information horizontally to other bacteria.