The findings can help advance the development of novel, targeted, naturally occurring probiotic therapy for patients with inflammatory bowel disease ... transduction pathway inhibition of NF ...

Researchers used genetic editing to uncover a pathway behind diseases like inflammatory bowel disorders. They say existing drugs could be used to interrupt the inflammation process and help treat ...

Specific protein signatures could predict a future diagnosis of Crohn disease and ulcerative colitis, potentially enabling ...

"Using genetics as a starting point, we've uncovered a pathway that appears to play a major role in IBD and other inflammatory diseases," said James Lee, group leader of the Genetic Mechanisms of ...

Dr. James Lee of the Francis Crick Institute will help guide development of PAS-004 for ETS2-driven diseases such as ...

“We clearly showed that turning up [the Pak2] pathway can inhibit colon inflammation ... into a different age of treatment for inflammatory bowel disease,” he explained.

"Inflammatory pathways in the body are likely activated at least five years before the onset of symptoms of IBD." James Lee, group leader of the Genetic Mechanisms of Disease Laboratory at the ...

Opens in a new tab or window ORLANDO -- Utilization of a "total telemedicine pathway" for inflammatory bowel disease (IBD) surgery saved a considerable amount of mileage and time for patients ...

Dr. Ma adds, "Our results show that BB1 prevented the TNF-α increase in intestinal tight junction permeability via a toll-like receptor (TLR)-2 signal transduction pathway inhibition of NF-kB p50 ...

Researchers have discovered a new biological pathway that is a principal driver of inflammatory bowel disease (IBD) and related conditions, and which can be targeted using existing drugs.