Cells rely on genes to guide their functions, with each gene containing both useful instructions (called exons) and non-essential segments (called introns). Splicing is the process by which cells trim ...

The financing will support the ongoing interventional Phase I/II ASTRA trial and the observational POLARIS study of SB-007.

The startup, which is backed by the venture arms of Sanofi, Roche and Novartis, is using dual adeno-associated viruses to ...

Spain’s SpliceBio will use $135 million from a series B round backed by Sanofi and Roche to advance its lead gene editing ...

The company’s intein-based technology is initially aimed at Stargardt disease, a type of macular degeneration.

Alternative splicing plays a pivotal role in defining cell phenotypes and physiology in multicellular eukaryotes, often distinguishing between cell types more accurately than gene expression. 1 During ...

The post Scientists Splice Gene Responsible For Vocalization In Humans Into Mice And Found Dramatic Changes In The Way They Squeaked first on TwistedSifter.

Alternative splicing is crucial for eukaryotic gene expression and influences protein function and regulation, with mis-splicing linked to numerous diseases. In this webinar, Dr. Megan L Noonan will ...

The study, published this week in Nature Genetics, shows that the biggest impact of alternative splicing may come via its role in regulating gene expression levels. The research team, led by Yang ...

According to the researchers, recognizing splice sites computationally is a crucial step in accurately assembling gene transcripts in modern genetics studies, where RNA sequencing experiments ...