mRNA-based drugs successfully delivered to intestine—without passing through the liver
Researchers at Tel Aviv University have achieved a breakthrough in drug delivery: they have successfully transported lipid ...
Medscape27d
Methadone Dose in the Treatment of Opiate Dependence
[13] It may be that methadone metabolism may be altered in late pregnancy, possibly due to the effect of progestins on hepatic drug metabolism. The management of methadone dosing during pregnancy ...
EurekAlert!1mon
Ferroptosis and intrinsic drug-induced liver injury by acetaminophen and other drugs: a critical evaluation and historical perspective
The reactive metabolite N-acetyl-p-benzoquinone imine (NAPQI), formed during APAP metabolism ... in liver injury. Broader Implications and Other Hepatotoxins Beyond APAP, several drugs and ...
Akero soars as drug shows it reverses scarring in liver disease patients
By Sriparna Roy (Reuters) -Akero Therapeutics shares gained 106% before the bell on Monday, after its lead drug showed it can ...
Weight loss drugs could help fight fatty liver disease
Next, Shulman and his team want to use their method to test the effects of these and other metabolism-related drugs on liver ...
Science Daily17d
A common antihistamine shows promise in treating liver complications of a rare disease complication
Researchers find that allergy medicine could help patients with a rare genetic disease avoid liver transplants.
STAT8d
Akero drug reverses liver scarring in study of severe MASH patients
Akero reported Monday strong results showing its drug efruxifermin reversed liver scarring in patients with cirrhosis caused ...
Medical Xpress20d
Decades-old allergy drug shows potential for treating liver complications in rare genetic disease
"Fortunately, we're not aware of similar chlorcyclizine metabolism differences ... by preventing liver damage at a much earlier stage. The antihistamine allergy drugs have been used safely for ...