The resulting hemoglobin is called HbS. HbS has different characteristics to normal adult hemoglobin, causing severe symptoms. HbS is structurally unstable. Upon high temperatures, dehydration ...
It turns out that, in these areas, HbS carriers have been naturally selected, because the trait confers some resistance to malaria. Their red blood cells, containing some abnormal hemoglobin ...
This is like coding new instructions into the cell. The old instructions for the abnormal hemoglobin S (HbS) are still there, but now the cell can make normal HbA (hemoglobin A) and HbS. The vector ...
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