Glucose is made from pyruvate, lactate, glycerol, glycerate 3-phosphate and amino acids and the process is called gluconeogenesis. Gluconeogenesis converts pyruvate to glucose-6-phosphate through ...

Indications: Measured enzymatically in blood or CSF as an index of impaired pyruvate metabolism due to defects of glucose oxidation (fed state) or gluconeogenesis (fasted). The ratio of lactate to ...

As a result, the ratios of G3P to DHAP, NADH to NAD, and lactate to pyruvate all increase in the cytoplasm. Gluconeogenesis decreases, and therefore secretion of glucose by the hepatocyte ...