Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such ...

Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival ...

Not all DNA looks like the familiar twisted ladder. Sometimes, parts of our genetic code fold into unusual shapes. One such structure, the ...

One example of these three-dimensional structures is G-quadruplex." G-quadruplex largely regulates switching between CD44v and CD44s contribute Working with human cells in culture, the researchers ...

Around 20,000 sites are associated with oncogenes in which the gene regulates cancer development and progression. The biological role of the G-quadruplex in cancer prognosis and pathogenesis has ...

This image is based on an x-ray crystal structure of a G-quadruplex formed from the DNA sequence found in human genomes. This image is based on an x-ray crystal structure of a G-quadruplex formed ...

But until now there has been no direct evidence of RNA G-quadruplex formation in living cells. In a new study which appears in Genome Biology, John Innes Center researchers investigated genetic ...

In patients with acute myeloid leukemia (AML) a combination of methods must be used to classify the disease, make therapeutic decisions, and determine the prognosis. However, this combined ...

but when measures of clinical risk are equivocal (e.g., intermediate expression of ER and intermediate histologic grade), these assays could guide clinical decisions. Results from studies of gene ...

One example of these three-dimensional structures is G-quadruplex." G-quadruplex largely regulates switching between CD44v and CD44s contribute Working with human cells in culture, the researchers ...