Role of mediator protein complex in transcription and gene expression. ScienceDaily . Retrieved May 22, 2025 from www.sciencedaily.com / releases / 2019 / 09 / 190910095404.htm ...

This process is regulated by transcription factors, a class of proteins that control gene expression by binding to DNA. However, binding is complex due to the tightly compacted structure of DNA ...

Viral replication is associated with the formation of a replication and transcription complex (RTC) in CoVs, from NSP1-16. The RTC synthesizes genomic RNA (gRNA) and subgenomic RNAs (sgRNAs ...

Backtracking refers to the retrograde movement of the RNA-dependent RNA polymerase (RdRp), which is the crucial enzyme within the SARS-CoV-2 replication-transcription complex. This enzyme ...

The key protein in the complex is the Islet-1 transcription factor, and Hunter, in a series of previous discoveries, has tracked down other proteins that join with Islet-1 to form the complex.

The RNP complex is extremely flexible, so scientists have historically had difficulty pinning down its full structure and mechanism. But this week, structural biologists report success in taking ...

Transcription factors (TFs) are the most essential protein group for the cellular development, differentiation and maintaining homeostasis. They drive complex patterns of gene expression in cells ...

The protein in question, TAF2, is part of the general transcription factor TFIID ... at gene promoters as part of the classical TFIID complex," explains Tanja Bhuiyan. "Instead, this flexible ...